I have found it very difficult to find a comfortable bra after having had breast cancer and also a bilateral reduction. I need to wear a small prosthesis in one cup and find sizing very difficult. I was actually a FF cup previously and am now a C cup. The problem is that the surgery is done underneath my breasts, but the spread or width of my breasts still relates to a FF cup. So have a 16C bra now with underwire that fits perfectly.The underwire stops it from riding up and the bra is wide enough in the cups to support side tissue. I guess that I am very lucky still to have normal looking breasts (aside from all the scar tissue) even though they are not quite proportional to the rest of my body. I probably am a B cup now, but because of the width of previous breasts I need to wear a C cup. I can't tell you just how comfortable the Lilly underwire bra is!